General guidelines

All research projects involving human beings, directly or indirectly, must be submitted to a Human Research Ethics Committee (REC). The submission of the project must be made by the authors via Plataforma Brasil. The REC evaluation protocol number must be mentioned in the Original Articles and Case Reports. Articles with no indication of the REC protocol are not published.

Also, the number of the Certificate of Presentation for Ethical Appraisal (CAAE) of Plataforma Brasil must be indicated in Original Articles and Case Reports carried out in Brazil, according to circular letters of the National Research Ethics Commission (Conep) of 2018. Articles that do not indicate the CAAE are not published.

The patient must sign the Informed Consent Form (ICF), and his/her decision to participate in the study will be informed and recorded voluntarily and without embarrassment. Every effort should be made to protect your privacy. Identifying information, including photos, should not be included in the manuscript.

The International Committee of Medical Journal Editors (ICMJE) clinical trial registration policy requires registration of all prospective clinical trials. Manuscripts will only be accepted for publication if they have received an identification number in one of the Clinical Trial Registries validated by the World Health Organization (WHO) and the ICMJE, whose addresses are available on the latter's website, such as, for example, www.ensaiosclinicos.gov.br or www.clinicaltrials.gov. The identification number must appear at the end of the abstract.

Experimental work involving animals must comply with the standards established by the Guide for the Care and Use of Laboratory Animals (Institute of Laboratory Animal Resources, National Academy of Sciences, Washington, DC, United States), of 1996, and by the Ethical Principles in Animal Experimentation (Brazilian College of Animal Experimentation – COBEA), of 1991.

Manuscripts must comply with the following guidelines: